この箱を開けてください。

this (something or someone close to the speaker (including the speaker), or ideas expressed by the speaker)

box; case; chest; package; pack; car (of a train, etc.); shamisen case; shamisen; public building; community building; man who carries a geisha's shamisen; receptacle for human waste; feces (faeces); counter for boxes (or boxed objects)

indicates direct object of action; indicates subject of causative expression; indicates an area traversed; indicates time (period) over which action takes place; indicates point of departure or separation of action; indicates object of desire, like, hate, etc.

to open; to bare; to expose; to stretch

to give; to confer; to bestow; to kindly do for one; to oblige; to favour; to favor