学校はいつ終わりますか。

school

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

to need; to want

indicates two contrasting actions; indicates possessive (often found in place names and compound words)

to finish; to end; to close

indicates a question (sometimes rhetorical); or; whether or not; some- (e.g. something, someone); indicates doubt, uncertainty, etc.; emphatic prefix; suffix forming adjectives or adverbs; in that way