君には愛想がつきたよ。

you; buddy; pal; monarch; ruler; sovereign; (one's) master

at (place, time); in; on; during; to (direction, state); toward; into; for (purpose); because of (reason); for; with; by; from; as (i.e. in the role of); per; in; for; a (e.g. "once a month"); and; in addition to; if; although

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

civility; courtesy; compliments; sociability; graces

indicates sentence subject (occasionally object); indicates possessive (esp. in literary expressions); but; however; still; and

to be lit (e.g. electricity comes on); to be lighted; to catch fire

indicates certainty, emphasis, contempt, request, etc.; used when calling out to someone; used to catch one's breath or get someone's attention; yo!