今では事情が変わってきた。

now; the present time; just now; soon; immediately; (one) more

indicates location of action; at; in; indicates time of action; indicates means of action; cause of effect; by; and then; so; indicates continuing action; indicates certainty, emphasis, etc.

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

circumstances; consideration; conditions; situation; reasons; state of affairs

indicates sentence subject (occasionally object); indicates possessive (esp. in literary expressions); but; however; still; and

to change; to be transformed; to be altered; to vary; to move to; to be different; to be uncommon; to be unusual