最後の最後まであきらめるな。

last; end; conclusion; latest; most recent; no sooner than; right after (often having negative consequences); one's final moments

indicates possessive; nominalizes verbs and adjectives; substitutes for "ga" in subordinate phrases; (at sentence-end, falling tone) indicates a confident conclusion; (at sentence-end) indicates emotional emphasis; (at sentence-end, rising tone) indicates question

until (a time); till; to; up to; to (a place); as far as; to (an extent); up to; so far as; even; only; merely

to give up; to abandon (hope, plans); to resign oneself (to)

(sentence end, mainly masc.) indicates emotion or emphasis; (used with masu stem verb) command; (used with dictionary form verb) prohibition