仕方がないよ。

way; method; means; resource; course

indicates sentence subject (occasionally object); indicates possessive (esp. in literary expressions); but; however; still; and

nonexistent; not being (there); unpossessed; unowned; not had; unique; indicates negation, inexperience, unnecessariness or impossibility; not ...; to not be...; to have not ...

indicates certainty, emphasis, contempt, request, etc.; used when calling out to someone; used to catch one's breath or get someone's attention; yo!