週末はどうするんだい。

weekend

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

how; in what way; how about

to do; to cause to become; to make (into); to turn (into); to serve as; to act as; to work as; to wear (clothes, a facial expression, etc.); to judge as being; to view as being; to think of as; to treat as; to use as; to decide on; to choose; to be sensed (of a smell, noise, etc.); to be (in a state, condition, etc.); to be worth; to cost; to pass (of time); to elapse; verbalizing suffix (applies to nouns noted in this dictionary with the part of speech "vs"); creates a humble verb (after a noun prefixed with "o" or "go"); to be just about to; to be just starting to; to try to; to attempt to

yes; yeah; uh huh; negative verb ending used in informal speech (abbr. of negative verb ending "nu"); abbr. of particle "no"; abbr. of particle "ni" (used especially when it precedes the verb "naru")

title; subject; theme; topic; problem (on a test); question; counter for questions (on a test)