大声で話してはいけない。

loud voice

indicates location of action; at; in; indicates time of action; indicates means of action; cause of effect; by; and then; so; indicates continuing action; indicates certainty, emphasis, etc.

to talk; to speak; to converse; to chat; to tell; to explain; to narrate; to mention; to describe; to discuss; to speak (a language)

if ... then; when; and; why don't you...?; the more (one does something); because; since