彼は週末によく家を空ける。

he; him; his; boyfriend

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

weekend

at (place, time); in; on; during; to (direction, state); toward; into; for (purpose); because of (reason); for; with; by; from; as (i.e. in the role of); per; in; for; a (e.g. "once a month"); and; in addition to; if; although

nicely; properly; well; skillfully; skilfully; frequently; often

house; residence; dwelling; family; household; lineage; family name

indicates direct object of action; indicates subject of causative expression; indicates an area traversed; indicates time (period) over which action takes place; indicates point of departure or separation of action; indicates object of desire, like, hate, etc.

to open (a door, etc.); to unwrap (e.g. parcel, package); to unlock; to open (for business, etc.); to empty; to remove; to make space; to make room; to move out; to clear out; to be away from (e.g. one's house); to leave (temporarily); to dawn; to grow light; to end (of a period, season); to begin (of the New Year); to leave (one's schedule) open; to make time (for); to make (a hole); to open up (a hole)