彼らの努力は実を結ばなかった。

they (usually male); them

indicates possessive; nominalizes verbs and adjectives; substitutes for "ga" in subordinate phrases; (at sentence-end, falling tone) indicates a confident conclusion; (at sentence-end) indicates emotional emphasis; (at sentence-end, rising tone) indicates question

great effort; exertion; endeavour; endeavor; effort

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

fruit; nut; seed; (in broth) pieces of meat, vegetable, etc.; content; substance

indicates direct object of action; indicates subject of causative expression; indicates an area traversed; indicates time (period) over which action takes place; indicates point of departure or separation of action; indicates object of desire, like, hate, etc.

to tie; to bind; to link; to bear (fruit); to close (e.g. deal); to confirm; to conclude; to connect (two distant places); to close tightly; to purse (e.g. lips); to unite (with); to ally; to join hands