あきらめるな。仕事に頑張れよ。

to give up; to abandon (hope, plans); to resign oneself (to)

(sentence end, mainly masc.) indicates emotion or emphasis; (used with masu stem verb) command; (used with dictionary form verb) prohibition

work; job; business; occupation; employment; vocation; task; work

at (place, time); in; on; during; to (direction, state); toward; into; for (purpose); because of (reason); for; with; by; from; as (i.e. in the role of); per; in; for; a (e.g. "once a month"); and; in addition to; if; although

to persevere; to persist; to keep at it; to hang on; to hold out; to do one's best; to insist that; to stick to (one's opinion); to remain in a place; to stick to one's post; to refuse to budge

indicates certainty, emphasis, contempt, request, etc.; used when calling out to someone; used to catch one's breath or get someone's attention; yo!