あなたはいつから忙しくしていますか。

you (referring to someone of equal or lower status); dear (what a wife calls a husband)

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

to need; to want

indicates two contrasting actions; indicates possessive (often found in place names and compound words)

from (e.g. time, place, numerical quantity); since; from (originator); by; because; since; out of (constituent, part); through (e.g. window, vestibule); after; since

busy; hectic; occupied; engaged

to do; to cause to become; to make (into); to turn (into); to serve as; to act as; to work as; to wear (clothes, a facial expression, etc.); to judge as being; to view as being; to think of as; to treat as; to use as; to decide on; to choose; to be sensed (of a smell, noise, etc.); to be (in a state, condition, etc.); to be worth; to cost; to pass (of time); to elapse; verbalizing suffix (applies to nouns noted in this dictionary with the part of speech "vs"); creates a humble verb (after a noun prefixed with "o" or "go"); to be just about to; to be just starting to; to try to; to attempt to

indicates a question (sometimes rhetorical); or; whether or not; some- (e.g. something, someone); indicates doubt, uncertainty, etc.; emphatic prefix; suffix forming adjectives or adverbs; in that way