あなたはとても疲れているようにみえます。

You look very tired.

あなたはとても疲(つか)れているようにみえます。

Anata wa totemo tsukareteiru yōni miemasu.

貴方 (あなた)

you (referring to someone of equal or lower status); dear (what a wife calls a husband)

は (は)

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

迚も (とても、とっても)

very; awfully; exceedingly; (not) at all; by no means; simply (cannot)

疲れる (つかれる)

to get tired; to tire; to be worn out (e.g. of well used objects); to starve

様に (ように)

in order to (e.g. meet goal); so that; take care (so as); hoping or wishing for something

見える (みえる)

to be seen; to be in sight; to look; to seem; to appear; to come

Readings: ヒ、つか.れる、 -づか.れ、つか.らす

Meanings: exhausted, tire, weary