あんなに走り回っているのに、彼が病気だなんてことがあるだろうか。

to that extent; to that degree

to run around

although; when; and yet; despite this; in spite of; even though; but even so; but even then; however; nevertheless; for all that; notwithstanding that; while; if only; I wish; I tell you; you should do; in order to

he; him; his; boyfriend

indicates sentence subject (occasionally object); indicates possessive (esp. in literary expressions); but; however; still; and

illness; disease; sickness

be; is; indicates past or completed action; indicates light imperative

such as; (things) like; exclamation

thing; matter; incident; occurrence; event; something serious; trouble; crisis; circumstances; situation; state of affairs; work; business; affair; after an inflectable word, creates a noun phrase indicating something the speaker does not feel close to; nominalizing suffix; pretending to ...; playing make-believe ...; alias; aka; nickname; alternative name; also known as

to be (usu. of inanimate objects); to exist; to live; to have; to be located; to be equipped with; to happen; to come about

indicates a question (sometimes rhetorical); or; whether or not; some- (e.g. something, someone); indicates doubt, uncertainty, etc.; emphatic prefix; suffix forming adjectives or adverbs; in that way