このひっきりなしの騒音は頭にくる。

this (something or someone close to the speaker (including the speaker), or ideas expressed by the speaker)

continually; continuously; incessantly

indicates possessive; nominalizes verbs and adjectives; substitutes for "ga" in subordinate phrases; (at sentence-end, falling tone) indicates a confident conclusion; (at sentence-end) indicates emotional emphasis; (at sentence-end, rising tone) indicates question

noise

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

head; hair (on one's head); mind; brains; intellect; leader; chief; boss; captain; top; tip; beginning; start; head; person; top structural component of a kanji

at (place, time); in; on; during; to (direction, state); toward; into; for (purpose); because of (reason); for; with; by; from; as (i.e. in the role of); per; in; for; a (e.g. "once a month"); and; in addition to; if; although

to gouge; to hollow out; to bore; to excavate; to scoop out; to greatly perturb; to cause emotional pain; to get to the bottom of things; to relentlessly bring the truth to light