この痛みはこれ以上我慢できない。

this (something or someone close to the speaker (including the speaker), or ideas expressed by the speaker)

pain; ache; soreness; grief; distress; damage; injury; wear; bruise; break

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

this (indicating an item near the speaker, the action of the speaker, or the current topic); this person (usu. indicating someone in one's in-group); now; here; I (me); certainly

not less than; ... and more; ... and upwards; beyond ... (e.g. one's means); further (e.g. nothing further to say); more than ... (e.g. cannot pay more than that); above-mentioned; foregoing; since ...; seeing that ...; this is all; that is the end; the end

patience; endurance; perseverance; tolerance; self-control; self-denial

to be able (in a position) to do; to be up to the task; to be ready; to be completed; to be made; to be built; to be good at; to be permitted (to do); to become intimate; to take up (with somebody); to grow; to be raised; to become pregnant