これらの指示をよく守りなさい。

these

indicates possessive; nominalizes verbs and adjectives; substitutes for "ga" in subordinate phrases; (at sentence-end, falling tone) indicates a confident conclusion; (at sentence-end) indicates emotional emphasis; (at sentence-end, rising tone) indicates question

indication; instruction; designation; directions

indicates direct object of action; indicates subject of causative expression; indicates an area traversed; indicates time (period) over which action takes place; indicates point of departure or separation of action; indicates object of desire, like, hate, etc.

nicely; properly; well; skillfully; skilfully; frequently; often

to protect; to guard; to defend; to keep (i.e. a promise); to abide (by the rules); to observe; to obey; to follow

to do