コンピューターの操作の仕方を知ってますか。

computer

indicates possessive; nominalizes verbs and adjectives; substitutes for "ga" in subordinate phrases; (at sentence-end, falling tone) indicates a confident conclusion; (at sentence-end) indicates emotional emphasis; (at sentence-end, rising tone) indicates question

operation; management; processing; manipulating to one's benefit; to operate; to manipulate; to fiddle (e.g. the books)

way; method; means; resource; course

indicates direct object of action; indicates subject of causative expression; indicates an area traversed; indicates time (period) over which action takes place; indicates point of departure or separation of action; indicates object of desire, like, hate, etc.

to be aware of; to know; to be conscious of; to cognize; to cognise; to notice; to feel; to understand; to comprehend; to grasp; to remember; to be acquainted with (a procedure); to experience; to go through; to learn; to be acquainted with (a person); to get to know; to concern

indicates a question (sometimes rhetorical); or; whether or not; some- (e.g. something, someone); indicates doubt, uncertainty, etc.; emphatic prefix; suffix forming adjectives or adverbs; in that way