それはどうしても我慢できない。

that (indicating an item or person near the listener, the action of the listener, or something on their mind); it; that time; then; there (indicating a place near the listener); you

topic marker particle; indicates contrast with another option (stated or unstated); adds emphasis

by all means; at any cost; no matter what; after all; in the long run; cravingly; at any rate; surely

patience; endurance; perseverance; tolerance; self-control; self-denial

to be able (in a position) to do; to be up to the task; to be ready; to be completed; to be made; to be built; to be good at; to be permitted (to do); to become intimate; to take up (with somebody); to grow; to be raised; to become pregnant